Only with corrective optics
Canon EF sits 18.50mm further from the sensor than Samsung NX. An adapter can only add distance, never remove it, so infinity focus is impossible without corrective glass in the adapter — which costs sharpness and usually a stop of light.
Coverage & framing. Samsung NX lenses are built for a APS-C imaging circle, which is smaller than Full frame. Expect heavy vignetting or a forced crop on a Canon EF body.