Only with corrective optics
Canon RF sits 2.30mm further from the sensor than Fujifilm X. An adapter can only add distance, never remove it, so infinity focus is impossible without corrective glass in the adapter — which costs sharpness and usually a stop of light.
Coverage & framing. Fujifilm X lenses are built for a APS-C imaging circle, which is smaller than Full frame. Expect heavy vignetting or a forced crop on a Canon RF body.